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Humboldt-Universität zu Berlin - IRI Life Sciences

Humboldt-Universität zu Berlin | IRI Life Sciences | Training | Summer School "Epigenetics meets mathematics"

IRI Summer School

Poster Summer School "Epigenetics meets mathematics"

Epigenetics meets mathematics

 

2nd - 8th July 2017

 

IRI Life Sciences

Humboldt-Universität zu Berlin

Berlin (Germany)

 

 

 

Please note that the application process is closed!

 

The IRI Summer School “Epigenetics meets mathematics“ aims to inspire experimentalists and theoreticians in epigenetics research each to engage with the other discipline.

 

The programme offers outstanding PhD students and Postdocs, who work experimentally or theoretically in epigenetics research, a comprehensive overview of current research combining theoretical biology and experimental epigenetics in lectures and workshops held by internationally renowned experts.

 

The summer school will comprise the following teaching contents that will be discussed from an experimental and a theoretical/ computational perspective in lectures, modelling workshops, and lab demonstrations:

 

  • Introduction to epigenetics and the use of mathematics in biology
     
  • Genomic features defining sites of epigenetic regulation: Predictive models using statistical learning
    Why is DNA sequence important to epigenetics? What are the experimental challenges in mapping binding sites? What are the modelling challenges in predicting binding sites?
     
  • In vivo, real time dynamics of epigenetic regulators: Kinetic ODE models
    Why is dynamic behaviour important to epigenetics? What insights does ODE modelling give? How can chromatin dynamics be visualized in vivo?
     
  • Nucleosome and chromatin dynamics, epigenetic memory and switching: Stochastic model
    Why is stochastic behaviour important to epigenetics? When is stochastic behaviour more appropriate than kinetic ODE modelling? Which information can be gained by stochastic modelling?
     
  • Chromosomal long-range interactions: Polymer models
    Why are long range interactions important to epigenetics? How is modelling used in this regard?
     

 

During the course the participants will also work in small, interdisciplinary groups on selected, cross-disciplinary topics in epigenetics, which will be presented and discussed during a student-led session.

 

In addition, the participants will also have the opportunity to present their own research in talks or during a poster session and to discuss with the invited experts and the other participants.